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The antibody against SLITRK6 was raised in rabbit using the Recombinant Human SLIT and NTRK-like protein 6 protein (621-821AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against SLITRK6 was raised in rabbit using the Recombinant Human SLIT and NTRK-like protein 6 protein (621-821AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human thyroid tissue using SLITRK6 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung tissue using SLITRK6 Antibody at dilution of 1:1002
Immunofluorescent analysis of HepG2 cells using SLITRK6 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-18311A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLITRK6 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human SLIT and NTRK-like protein 6 protein (621-821AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H5Y7 |
Uniprot Id
Q9H5Y7
Target Species
Human
Target Name
SLITRK6
Target Full Name
SLIT and NTRK-like protein 6
Target Function
Regulator of neurite outgrowth required for normal hearing and vision.
Target Involvement
Deafness and myopia (DFNMYP)
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Protein Families
SLITRK family
Target Tissue Specificity
In adult brain, highly expressed in putamen with no expression in cerebral cortex. Expressed in adult and fetal lung and fetal liver. Also expressed at high levels in some brain tumors including medulloblastomas and primitive neuroectodermal tumors.
Target Synonyms
4832410J21Rik; DFNMYP; MGC119595; MGC119596; MGC119597; OTTHUMP00000066012; SLIK6_HUMAN; SLIT and NTRK like family member 6; SLIT and NTRK like protein 6; SLIT and NTRK-like protein 6; Slit and trk like 6; Slit and trk like gene 6; SLITRK 6; Slitrk6
Target Background
This gene encodes a member of the SLITRK protein family. Members of this family are integral membrane proteins that are characterized by two N-terminal leucine-rich repeat (LRR) domains and a C-terminal region that shares homology with trk neurotrophin receptors. This protein functions as a regulator of neurite outgrowth required for normal hearing and vision. Mutations in this gene are a cause of myopia and deafness.
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