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The antibody against SNCAIP was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human Synphilin-1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against SNCAIP was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human Synphilin-1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
$167.00
Western Blot analysis of COLO205 cells using Synphilin-1 Polyclonal Antibody
| Cat.No | ADC-37533A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SNCAIP |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the C-terminal region of Human Synphilin-1. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y6H5 |
Uniprot Id
Q9Y6H5
Target Species
Human
Target Name
SNCAIP
Target Full Name
Synphilin-1
Target Function
Isoform 2 inhibits the ubiquitin ligase activity of SIAH1 and inhibits proteasomal degradation of target proteins. Isoform 2 inhibits autoubiquitination and proteasomal degradation of SIAH1, and thereby increases cellular levels of SIAH. Isoform 2 modulates SNCA monoubiquitination by SIAH1.
Target Involvement
Parkinson disease (PARK)
Target Subcellular Location
Cytoplasm. Note=Detected in cytoplasmic inclusion bodies, together with SNCA.
Target Tissue Specificity
Detected in brain (at protein level). Widely expressed, with highest levels in brain, heart and placenta.
Target Synonyms
Alpha synuclein interacting protein; Alpha-synuclein-interacting protein; MGC39814; SNCAIP; SNCAP_HUMAN; Sph1; Synphilin-1; Synphilin1; Synuclein alpha interacting protein (synphilin); Synuclein alpha interacting protein; SYPH 1
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