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The antibody against SPIC was raised in rabbit using the Recombinant Human Transcription factor Spi-C protein (1-248AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against SPIC was raised in rabbit using the Recombinant Human Transcription factor Spi-C protein (1-248AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human breast cancer using SPIC Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human small intestine tissue using SPIC Antibody at dilution of 1:1002
| Cat.No | ADC-23440A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SPIC |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Transcription factor Spi-C protein (1-248AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8N5J4 |
Uniprot Id
Q8N5J4
Target Species
Human
Target Name
SPIC
Target Full Name
Transcription factor Spi-C
Target Function
Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression.
Target Subcellular Location
Nucleus.
Target Protein Families
ETS family
Target Tissue Specificity
Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver.
Target Synonyms
AU019198; C76795; MGC40611; MGC80555; Prf; Pu.1 related factor; Spi C; Spi C transcription factor; Spi-C transcription factor (Spi-1/PU.1 related); spiC; SPIC_HUMAN; Transcription factor Spi-C
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