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The antibody against SPOPL was raised in rabbit using the Recombinant Human Speckle-type POZ protein-like protein (1-120AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against SPOPL was raised in rabbit using the Recombinant Human Speckle-type POZ protein-like protein (1-120AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-05855A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SPOPL |
| Target Synonyms | SPOPL antibody; Speckle-type POZ protein-like antibody; HIB homolog 2 antibody; Roadkill homolog 2 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Speckle-type POZ protein-like protein (1-120AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6IQ16 |
Uniprot Id
Q6IQ16
Target Species
Human
Target Name
SPOPL
Target Full Name
Speckle-type POZ protein-like
Target Function
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, but with relatively low efficiency. Cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL are less efficient than ubiquitin ligase complexes containing only SPOP. May function to down-regulate the activity of cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes that contain SPOP.
Target Subcellular Location
Nucleus.
Target Protein Families
Tdpoz family
Target Synonyms
SPOPL; Speckle-type POZ protein-like; HIB homolog 2; Roadkill homolog 2
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