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The antibody against SRP54 was raised in rabbit using the Fusion protein of Human SRP54 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against SRP54 was raised in rabbit using the Fusion protein of Human SRP54 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-29282A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SRP54 |
| Target Synonyms | Signal recognition particle 54 kDa protein antibody; Signal recognition particle 54kDa antibody; SRP 54 antibody; SRP54 antibody; SRP54_HUMAN antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human SRP54 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P61011 |
Uniprot Id
P61011
Target Species
Human
Target Name
SRP54
Target Full Name
Signal recognition particle subunit SRP54
Target Function
Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Plays a role in proliferation and differentiation of granulocytic cells, neutrophils migration capacity and exocrine pancreas development.
Target Subcellular Location
Nucleus speckle. Cytoplasm. Endoplasmic reticulum.
Target Protein Families
GTP-binding SRP family, SRP54 subfamily
Target Research Area
Signal Transduction
Target Synonyms
Signal recognition particle 54 kDa protein; Signal recognition particle 54kDa; SRP 54; SRP54; SRP54_HUMAN
Target Background
Enables several functions, including 7S RNA binding activity; endoplasmic reticulum signal peptide binding activity; and guanyl ribonucleotide binding activity. Contributes to GTPase activity. Involved in granulocyte differentiation and protein targeting to ER. Located in cytosol and nucleus. Part of signal recognition particle, endoplasmic reticulum targeting. Implicated in severe congenital neutropenia 8.
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