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Rabbit anti-Human SRSF4 Polyclonal Antibody

The antibody against SRSF4 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human SRp75. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

ADC-37567A

The antibody against SRSF4 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human SRp75. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-37567A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSRSF4
Target Synonyms75-KD antibody; SRP001LB antibody; SRP75 antibody; Srsf4 antibody; SRSF4_HUMAN antibody, arginine/serine rich, arginine/serine rich 4 antibody; Splicing factorFormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human SRp75.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ08170
Background Information
  • Uniprot Id

    Q08170

  • Target Species

    Human

  • Target Name

    SRSF4

  • Target Full Name

    Serine/arginine-rich splicing factor 4

  • Target Function

    Plays a role in alternative splice site selection during pre-mRNA splicing. Represses the splicing of MAPT/Tau exon 10.

  • Target Subcellular Location

    Nucleus speckle.

  • Target Protein Families

    Splicing factor SR family

  • Target Synonyms

    SFRS4; SRP75; SRSF4

  • Target Background

    Enables RNA binding activity. Involved in negative regulation of mRNA splicing, via spliceosome. Located in nuclear speck. Biomarker of Down syndrome; acute myeloid leukemia; clear cell renal cell carcinoma; and colon adenocarcinoma.

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