Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against StAR was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 64-285 of human StAR (NP_000340.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against StAR was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 64-285 of human StAR (NP_000340.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-12950A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | STAR |
| Target Synonyms | STARD1; StAR | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse testis, Rat testis | Application | ELISA, WB, IF/ICC |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 64-285 of human StAR (NP_000340.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P49675 | Immunogen Sequence |
Uniprot Id
P49675
Target Species
Human
Target Name
STAR
Target Full Name
Steroidogenic acute regulatory protein, mitochondrial
Target Function
Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.
Target Involvement
Adrenal hyperplasia 1 (AH1)
Target Subcellular Location
Mitochondrion.
Target Tissue Specificity
Expressed in gonads, adrenal cortex and kidney.
Target Synonyms
Cholesterol trafficker; Luteinizing hormone induced protein; mitochondrial; Mitochondrial steroid acute regulatory protein; StAR; StAR related lipid transfer (START) domain containing 1; STAR_HUMAN; StARD1; START domain containing 1; START domain containing protein 1; START domain-containing protein 1; Steroid acute regulatory protein; Steroidogenic acute regulator; Steroidogenic acute regulatory protein; Steroidogenic acute regulatory protein mitochondrial
Target Background
The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
