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The antibody against SUOX was raised in rabbit using the Recombinant Human Sulfite oxidase, mitochondrial protein (80-545AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against SUOX was raised in rabbit using the Recombinant Human Sulfite oxidase, mitochondrial protein (80-545AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human liver tissue using SUOX Antibody at dilution of 1:1002
| Cat.No | ADC-49985A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SUOX |
| Target Synonyms | EC 1.8.3.1 antibody; mitochondrial antibody; Sulfite oxidase antibody; Sulfite oxidase mitochondrial antibody; Sulfite oxidase; mitochondrial precursor antibody; Suox antibody; SUOX_HUMAN antibody | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Sulfite oxidase, mitochondrial protein (80-545AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P51687 |
Uniprot Id
P51687
Target Species
Human
Target Name
SUOX
Target Full Name
Sulfite oxidase, mitochondrial
Target Involvement
Isolated sulfite oxidase deficiency (ISOD)
Target Subcellular Location
Mitochondrion intermembrane space.
Target Research Area
Metabolism
Target Synonyms
EC 1.8.3.1; mitochondrial; Sulfite oxidase; Sulfite oxidase mitochondrial ; Sulfite oxidase; mitochondrial precursor; Suox; SUOX_HUMAN
Target Background
Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins.
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