Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against TBC1D7 was raised in rabbit using the Recombinant Human TBC1 domain family member 7 protein (1-293AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against TBC1D7 was raised in rabbit using the Recombinant Human TBC1 domain family member 7 protein (1-293AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human liver tissue using TBC1D7 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human prostate tissue using TBC1D7 Antibody at dilution of 1:1002
Immunofluorescent analysis of HepG2 cells using TBC1D7 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-14994A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TBC1D7 |
| Target Synonyms | TBC1D7 antibody; TBC7 antibody; HSPC239 antibody; TBC1 domain family member 7 antibody; Cell migration-inducing protein 23 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human TBC1 domain family member 7 protein (1-293AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9P0N9 |
Uniprot Id
Q9P0N9
Target Species
Human
Target Name
TBC1D7
Target Full Name
TBC1 domain family member 7
Target Function
Component of the TSC-TBC complex, that contains TBC1D7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protein (GAP) activity toward RHEB in response to alterations in specific cellular growth conditions. The small GTPase RHEB is a direct activator of the protein kinase activity of mTORC1 and the TSC-TBC complex acts as a negative regulator of mTORC1 signaling cascade by acting as a GAP for RHEB. Participates in the proper sensing of growth factors and glucose, but not amino acids, by mTORC1. It is unclear whether TBC1D7 acts as a GTPase-activating protein and additional studies are required to answer this question.
Target Involvement
Macrocephaly/megalencephaly syndrome, autosomal recessive (MGCPH)
Target Subcellular Location
Cytoplasmic vesicle. Note=Localizes in the cytoplasmic vesicles of the endomembrane in association with TSC1-TSC2 complex.
Target Tissue Specificity
Highly expressed in heart, and slightly in kidney, liver and placenta.
Target Synonyms
TBC1D7; TBC7; HSPC239; TBC1 domain family member 7; Cell migration-inducing protein 23
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
