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Rabbit anti-Human TBL1Y Polyclonal Antibody

The antibody against TBL1Y was raised in rabbit using the Fusion protein of Human TBL1Y as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-29009A

The antibody against TBL1Y was raised in rabbit using the Fusion protein of Human TBL1Y as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-29009A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTBL1Y
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBS
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human TBL1YTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9BQ87
Background Information
  • Uniprot Id

    Q9BQ87

  • Target Species

    Human

  • Target Name

    TBL1Y

  • Target Full Name

    F-box-like/WD repeat-containing protein TBL1Y

  • Target Function

    F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    WD repeat EBI family

  • Target Tissue Specificity

    Fetal brain and prostate. Expressed in the cochlear spiral ganglion neurons, and in outer and inner hair cells.

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