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The antibody against TFPI2 was raised in rabbit using the Fusion protein of Human TFPI2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against TFPI2 was raised in rabbit using the Fusion protein of Human TFPI2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-31274A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TFPI2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human TFPI2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P48307 |
Uniprot Id
P48307
Target Species
Human
Target Name
TFPI2
Target Full Name
Tissue factor pathway inhibitor 2
Target Function
May play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effect on thrombin.
Target Subcellular Location
Secreted.
Target Tissue Specificity
Umbilical vein endothelial cells, liver, placenta, heart, pancreas, and maternal serum at advanced pregnancy.
Target Synonyms
Placental protein 5; PP5; REF1; Retinal pigment epithelium cell factor 1; TFPI 2; TFPI-2; TFPI2; TFPI2 PEN; TFPI2_HUMAN; Tissue factor pathway inhibitor 2
Target Background
This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants.
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