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The antibody against TLE2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human TLE2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against TLE2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human TLE2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
$167.00
| Cat.No | ADC-33915A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TLE2 |
| Target Synonyms | Drosophila) antibody; Transducin-like enhancer of split 2, homolog of Drosophila E(sp1) antibody; Transducin like enhancer protein 2 antibody; Transducin-like enhancer of split 2 (E(sp1) homolog, homolog of Drosophila E(spl) antibody; Transducin-like enhancer protein 2 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human TLE2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q04725 |
Uniprot Id
Q04725
Target Species
Human
Target Name
TLE2
Target Full Name
Transducin-like enhancer protein 2
Target Function
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
Target Subcellular Location
Nucleus.
Target Protein Families
WD repeat Groucho/TLE family
Target Tissue Specificity
In all tissues examined, mostly in heart, brain, and muscle.
Target Synonyms
ESG; ESG2; GRG2; TLE2
Target Background
Enables transcription corepressor activity. Involved in negative regulation of canonical Wnt signaling pathway and negative regulation of transcription, DNA-templated. Located in focal adhesion and nuclear body.
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