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The antibody against TLN2 was raised in rabbit using the Recombinant Human Talin-2 protein (88-406AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against TLN2 was raised in rabbit using the Recombinant Human Talin-2 protein (88-406AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human placenta tissue using TLN2 Antibody at dilution of 1:1002
| Cat.No | ADC-49532A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TLN2 |
| Target Synonyms | DKFZp451B1011 antibody; DKFZp686I0976 antibody; DKFZp686K0979 antibody; ILWEQ antibody; KIAA0320 antibody; Talin-2 antibody; talin2 antibody; TLN 2 antibody; TLN2 antibody; TLN2_HUMAN antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Talin-2 protein (88-406AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y4G6 |
Uniprot Id
Q9Y4G6
Target Species
Human
Target Name
TLN2
Target Full Name
Talin-2
Target Function
As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity.
Target Subcellular Location
Cytoplasm. Cell junction, focal adhesion. Cell junction, synapse. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton.
Target Research Area
Signal Transduction
Target Synonyms
DKFZp451B1011; DKFZp686I0976; DKFZp686K0979; ILWEQ; KIAA0320; Talin-2; talin2; TLN 2; TLN2; TLN2_HUMAN
Target Background
This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. This protein has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton.
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