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Rabbit anti-Human TMIGD2 Polyclonal Antibody

The antibody against TMIGD2 was raised in rabbit using the Recombinant Human Transmembrane and immunoglobulin domain-containing protein 2 protein (23-150AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.

ADC-11706A

The antibody against TMIGD2 was raised in rabbit using the Recombinant Human Transmembrane and immunoglobulin domain-containing protein 2 protein (23-150AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.

$299.00

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Specifications


Cat.No ADC-11706A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTMIGD2
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Transmembrane and immunoglobulin domain-containing protein 2 protein (23-150AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ96BF3
Background Information
  • Uniprot Id

    Q96BF3

  • Target Species

    Human

  • Target Name

    TMIGD2

  • Target Full Name

    Transmembrane and immunoglobulin domain-containing protein 2

  • Target Function

    Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.

  • Target Subcellular Location

    Cell membrane; Single-pass type I membrane protein.

  • Target Tissue Specificity

    Widely expressed, mainly by epithelial and endothelial cells, including bronchial epithelial cells of lung, breast glandular and lobular epithelia cells, urothelium of the bladder, skin epidermis, epithelium of gastrointestinal, rectum, endometrial glands

  • Target Synonyms

    CD28H; IGPR 1; IGPR1; immunoglobulin and proline-rich receptor 1; immunoglobulin-containing and proline-rich receptor 1; TMIG2_HUMAN; TMIGD2; Transmembrane and immunoglobulin domain containing 2; Transmembrane and immunoglobulin domain-containing protein 2; transmembrane and immunoglobulin domain-containing protein 2 variant 2; transmembrane and immunoglobulin domain-containing protein 2 variant 3; UNQ3059/PRO9879

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