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Rabbit anti-Human TPI1 Polyclonal Antibody

The antibody against TPI1 was raised in rabbit using the Human TPI1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-51537A

The antibody against TPI1 was raised in rabbit using the Human TPI1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ADC-51537A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTPI1
Target SynonymsTPI1 antibody; TPI antibody; Triosephosphate isomerase antibody; TIM antibody; EC 5.3.1.1 antibody; Methylglyoxal synthase antibody; EC 4.2.3.3 antibody; Triose-phosphate isomerase antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium AzidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman TPI1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP60174
Background Information
  • Uniprot Id

    P60174

  • Target Species

    Human

  • Target Name

    TPI1

  • Target Full Name

    Triosephosphate isomerase

  • Target Function

    Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.; It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.

  • Target Involvement

    Triosephosphate isomerase deficiency (TPID)

  • Target Subcellular Location

    Cytoplasm.

  • Target Protein Families

    Triosephosphate isomerase family

  • Target Synonyms

    TPI1; TPI; Triosephosphate isomerase; TIM; EC 5.3.1.1; Methylglyoxal synthase; EC 4.2.3.3; Triose-phosphate isomerase

  • Target Background

    This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants.

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