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The antibody against TRMT2B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human TRMT2B (NP_079193.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against TRMT2B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human TRMT2B (NP_079193.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-04109A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TRMT2B |
| Target Synonyms | CXorf34; dJ341D10.3; TRMT2B | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | MCF7, NCI-H460, Raji, SW480, U-87MG | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human TRMT2B (NP_079193.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q96GJ1 | Immunogen Sequence |
Uniprot Id
Q96GJ1
Target Species
Human
Target Name
TRMT2B
Target Full Name
tRNA (uracil-5-)-methyltransferase homolog B
Target Function
Probable S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNA. May also have a role in tRNA stabilization or maturation.
Target Protein Families
Class I-like SAM-binding methyltransferase superfamily, RNA M5U methyltransferase family
Target Synonyms
TRMT2B; CXorf34; tRNA; uracil(54)-C(5))-methyltransferase homolog; EC 2.1.1.35; TRM2 homolog
Target Background
This gene encodes a homolog of the TRM2 gene in S. cerevisiae. The yeast gene encodes a tRNA methyltransferase that plays a role in tRNA maturation. The yeast protein also has endo-exonuclease activity and may be involved in DNA double strand break repair. Alternative splicing results in multiple transcripts encoding different isoforms.
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