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The antibody against TSTA3 was raised in rabbit using the Recombinant Human GDP-L-fucose synthase protein (1-314AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against TSTA3 was raised in rabbit using the Recombinant Human GDP-L-fucose synthase protein (1-314AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
Immunofluorescent analysis of Hela cells using TSTA3 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-50469A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TSTA3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human GDP-L-fucose synthase protein (1-314AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q13630 |
Uniprot Id
Q13630
Target Species
Human
Target Name
GFUS
Target Full Name
GDP-L-fucose synthase
Target Function
Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
Target Protein Families
NAD(P)-dependent epimerase/dehydratase family, Fucose synthase subfamily
Target Synonyms
3 5 epimerase/4 reductase; 5-epimerase-4-reductase; anti TSTA3; EC 1.1.1.271; FCL_HUMAN; FX; GDP 4 keto 6 deoxy D mannose 3 5 epimerase 4 reductase; GDP 4 keto 6 deoxy D mannose epimerase reductase; GDP L fucose synthase; GDP-4-keto-6-deoxy-D-mannose-3; GDP-L-fucose synthase; P35B; Protein FX; Red cell NADP(H) binding protein; Red cell NADP(H)-binding protein; SDR4E1; Short chain dehydrogenase/reductase family 4E member 1; Short-chain dehydrogenase/reductase family 4E member 1; Tissue specific transplantation antigen 3; Tissue specific transplantation antigen P35B; TSTA3; TSTA3
Target Background
Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.
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