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Rabbit anti-Human VAMP4 Polyclonal Antibody

The antibody against VAMP4 was raised in rabbit using the Synthesized peptide derived from Human VAMP-4 around the non-phosphorylation site of S30. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IF, ELISA.

ADC-33476A

The antibody against VAMP4 was raised in rabbit using the Synthesized peptide derived from Human VAMP-4 around the non-phosphorylation site of S30. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IF, ELISA.

$167.00

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Specifications


Cat.No ADC-33476A ClonalityPolyclonal
Host SpeciesRabbitTarget NameVAMP4
Target SynonymsVAMP4; Vesicle-associated membrane protein 4; VAMP-4FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, IF
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from Human VAMP-4 around the non-phosphorylation site of S30.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO75379
Background Information
  • Uniprot Id

    O75379

  • Target Species

    Human

  • Target Name

    VAMP4

  • Target Full Name

    Vesicle-associated membrane protein 4

  • Target Function

    Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule.

  • Target Subcellular Location

    Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Note=Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG). Not found on the mature secretory organelles.

  • Target Protein Families

    Synaptobrevin family

  • Target Synonyms

    VAMP4; Vesicle-associated membrane protein 4; VAMP-4

  • Target Background

    Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport.

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