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Rabbit anti-Human WDYHV1 Polyclonal Antibody

The antibody against WDYHV1 was raised in rabbit using the Recombinant Human Protein N-terminal glutamine amidohydrolase protein (1-205AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

ADC-22307A

The antibody against WDYHV1 was raised in rabbit using the Recombinant Human Protein N-terminal glutamine amidohydrolase protein (1-205AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

$299.00

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Specifications


Cat.No ADC-22307A ClonalityPolyclonal
Host SpeciesRabbitTarget NameWDYHV1
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Protein N-terminal glutamine amidohydrolase protein (1-205AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ96HA8
Background Information
  • Uniprot Id

    Q96HA8

  • Target Species

    Human

  • Target Name

    NTAQ1

  • Target Full Name

    Protein N-terminal glutamine amidohydrolase

  • Target Function

    Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.

  • Target Subcellular Location

    Cytoplasm, cytosol. Nucleus.

  • Target Protein Families

    NTAQ1 family

  • Target Synonyms

    WDYHV1; C8orf32; NTAQ1; Protein N-terminal glutamine amidohydrolase; EC 3.5.1.122; Protein NH2-terminal glutamine deamidase; N-terminal Gln amidase; Nt(Q)-amidase; WDYHV motif-containing protein 1

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