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The antibody against ZFYVE16 was raised in rabbit using the Recombinant Human Zinc finger FYVE domain-containing protein 16 protein (1-280AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC, IF.
The antibody against ZFYVE16 was raised in rabbit using the Recombinant Human Zinc finger FYVE domain-containing protein 16 protein (1-280AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human kidney tissue using ZFYVE16 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human heart tissue using ZFYVE16 Antibody at dilution of 1:1002
Immunofluorescent analysis of Hela cells using ZFYVE16 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-16976A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ZFYVE16 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Zinc finger FYVE domain-containing protein 16 protein (1-280AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q7Z3T8 |
Uniprot Id
Q7Z3T8
Target Species
Human
Target Name
ZFYVE16
Target Full Name
Zinc finger FYVE domain-containing protein 16
Target Function
May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes.
Target Subcellular Location
Cytoplasm. Early endosome membrane; Peripheral membrane protein. Note=Localized to early endosomes. Membrane-associated, probably via its association with phosphatidylinositol 3-phosphate (PI3P).
Target Tissue Specificity
Widely expressed. Highly expressed in kidney, placenta and lung. Expressed at intermediate level in heart, brain, skeletal muscle, spleen and liver. Weakly expressed in colon, thymus and peripheral blood lymphocytes.
Target Synonyms
AI035632; B130024H06Rik; B130031L15; DKFZp686E13162; Endofin; Endosomal associated FYVE domain protein; Endosome associated FYVE domain protein; Endosome-associated FYVE domain protein; KIAA0305; KIAA0305,; mKIAA0305; OTTMUSP00000029589; RGD1564784; ZFY16_HUMAN; ZFYVE16; Zinc finger FYVE domain containing protein 16; Zinc finger FYVE domain-containing protein 16; Zinc finger; FYVE domain containing 16
Target Background
This gene encodes an endosomal protein that belongs to the FYVE zinc finger family of proteins. The encoded protein is thought to regulate membrane trafficking in the endosome. This protein functions as a scaffold protein in the transforming growth factor-beta signaling pathway and is involved in positive and negative feedback regulation of the bone morphogenetic protein signaling pathway. Alternate splicing results in multiple transcript variants.
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