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Rabbit anti-Human ZP3 Polyclonal Antibody

The antibody against ZP3 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 246-345 of human ZP3 (NP_001103824.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-11161A

The antibody against ZP3 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 246-345 of human ZP3 (NP_001103824.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

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Specifications


Cat.No ADA-11161A ClonalityPolyclonal
Host SpeciesRabbitTarget NameZP3
Target SynonymsZPC; ZP3A; ZP3B; Zp-3; OOMD3; OZEMA3; ZP3FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLaApplicationELISA, WB, IF/ICC

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 246-345 of human ZP3 (NP_001103824.1).Target SpeciesHuman
Immunogen SequenceDASSAFKVPRPGPDTLQFTVDVFHFANDSRNMIYITCHLKVTLAEQDPDELNKACSFSKPSNSWFPVEGSADICQCCNKGDCGTPSHSRRQPHVMSQWSRUniprot IDP21754
Background Information
  • Uniprot Id

    P21754

  • Target Species

    Human

  • Target Name

    ZP3

  • Target Full Name

    Zona pellucida sperm-binding protein 3

  • Target Function

    Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.

  • Target Involvement

    Oocyte maturation defect 3 (OOMD3)

  • Target Subcellular Location

    [Processed zona pellucida sperm-binding protein 3]: Zona pellucida.; Cell membrane; Single-pass type I membrane protein.

  • Target Protein Families

    ZP domain family, ZPC subfamily

  • Target Tissue Specificity

    Expressed in oocytes (at protein level).

  • Target Research Area

    Developmental Biology

  • Target Synonyms

    HUMZP3; Processed zona pellucida sperm-binding protein 3; Sperm receptor; zona pellucida glycoprotein 3 (sperm receptor); Zona pellucida glycoprotein 3; zona pellucida glycoprotein 3A (sperm receptor); Zona pellucida glycoprotein ZP3; Zona pellucida protein C; Zona pellucida sperm binding protein 3 precursor; Zp-3; ZP3 372; ZP3 424; ZP3 474; ZP3; ZP3_HUMAN; ZP3A; ZP3A/ZP3B; ZP3B; ZPC

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