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The antibody against ZRANB1 was raised in rabbit using the Recombinant Human Ubiquitin thioesterase ZRANB1 protein (111-397AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against ZRANB1 was raised in rabbit using the Recombinant Human Ubiquitin thioesterase ZRANB1 protein (111-397AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
Western Blot | Positive WB detected in: Hela whole cell lysate, Raji whole cell lysate, Jurkat whole cell lysate, 293T whole cell lysate, K562 whole cell lysate, SH-SY5Y whole cell lysate, HL-60 whole cell lysate | All lanes: ZRANB1 antibody at 1:2000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 81 kDa | Observed band size: 81 kDa
| Cat.No | ADC-02359A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ZRANB1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Ubiquitin thioesterase ZRANB1 protein (111-397AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UGI0 |
Uniprot Id
Q9UGI0
Target Species
Human
Target Name
ZRANB1
Target Full Name
Ubiquitin thioesterase ZRANB1
Target Function
Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling.
Target Subcellular Location
Cytoplasm. Nucleus. Note=Enriched in punctate localization in the cytoplasm.
Target Protein Families
Peptidase C64 family
Target Tissue Specificity
Widely expressed.
Target Research Area
Others
Target Synonyms
DKFZp762P2216; hTrabid; Trabid; TRAF-binding protein domain; Ubiquitin thioesterase ZRANB1; Zinc finger Ran-binding domain-containing protein 1; ZRAN1_HUMAN; ZRANB1
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