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The antibody against Apoe was raised in rabbit using the Recombinant Mouse Apolipoprotein E protein (19-311AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against Apoe was raised in rabbit using the Recombinant Mouse Apolipoprotein E protein (19-311AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-50746A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | APOE |
| Target Synonyms | ApoeApolipoprotein E antibody; Apo-E antibody | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 0.1mol/L NaCl, 15mmol/L NaN3, PH7.2 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Mouse Apolipoprotein E protein (19-311AA) | Target Species | Mus musculus (Mouse) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P08226 |
Uniprot Id
P08226
Target Species
Mouse
Target Name
APOE
Target Full Name
Apolipoprotein E
Target Function
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL). It also binds a wide range of cellular receptors including the LDL receptor/LDLR and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles. Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.
Target Subcellular Location
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
Target Protein Families
Apolipoprotein A1/A4/E family
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