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The antibody against Cobra venom factor was raised in rabbit using the Recombinant Naja kaouthia Cobra venom factor protein (733-984AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against Cobra venom factor was raised in rabbit using the Recombinant Naja kaouthia Cobra venom factor protein (733-984AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-11677A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Cobra venom factor |
| Form | Liquid | Species Reactivity | Naja kaouthia |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Naja kaouthia Cobra venom factor protein (733-984AA) | Target Species | Naja kaouthia |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q91132 |
Uniprot Id
Q91132
Target Species
Naja kaouthia
Target Function
Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely resistant to the actions of complement regulatory factors H (CFH) and I (CFI). Therefore, CVF continuously activates complement resulting in the depletion of complement activity.
Target Subcellular Location
Secreted.
Target Protein Families
Venom complement C3 homolog family
Target Tissue Specificity
Expressed by the venom gland.
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