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The antibody against DNAH1 was raised in rabbit using the Recombinant Human Dynein heavy chain 1, axonemal protein (2225-2407AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against DNAH1 was raised in rabbit using the Recombinant Human Dynein heavy chain 1, axonemal protein (2225-2407AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human prostate cancer using DNAH1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue using DNAH1 Antibody at dilution of 1:1002
Immunofluorescent analysis of HepG2 cells using DNAH1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-14969A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DNAH1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Dynein heavy chain 1, axonemal protein (2225-2407AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9P2D7 |
Uniprot Id
Q9P2D7
Target Species
Human
Target Name
DNAH1
Target Full Name
Dynein axonemal heavy chain 1
Target Function
Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme.
Target Involvement
Spermatogenic failure 18 (SPGF18); Ciliary dyskinesia, primary, 37 (CILD37)
Target Subcellular Location
Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum.
Target Protein Families
Dynein heavy chain family
Target Tissue Specificity
Expressed primarily in trachea and testis, 2 tissues containing axonemal structures. Also expressed in brain.
Target Synonyms
DNAH1; DHC7; DNAHC1; KIAA1410; Dynein heavy chain 1; axonemal; Axonemal beta dynein heavy chain 1; Ciliary dynein heavy chain 1; Heat shock regulated protein 1; HSRF-1; hDHC7
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