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The antibody against TPK1 was raised in rabbit using the Recombinant Human Thiamin pyrophosphokinase 1 protein (1-243AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF, IP.
The antibody against TPK1 was raised in rabbit using the Recombinant Human Thiamin pyrophosphokinase 1 protein (1-243AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF, IP.
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Immunohistochemistry of paraffin-embedded human kidney tissue using TPK1 Antibody at dilution of 1:1002
| Cat.No | ADC-16465A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TPK1 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB, IP | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Thiamin pyrophosphokinase 1 protein (1-243AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H3S4 |
Uniprot Id
Q9H3S4
Target Species
Human
Target Name
TPK1
Target Full Name
Thiamine pyrophosphokinase 1
Target Function
Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Can also catalyze the phosphorylation of pyrithiamine to pyrithiamine pyrophosphate.
Target Involvement
Thiamine metabolism dysfunction syndrome 5, episodic encephalopathy type (THMD5)
Target Protein Families
Thiamine pyrophosphokinase family
Target Tissue Specificity
Detected in heart, kidney, testis, small intestine and peripheral blood leukocytes, and at very low levels in a variety of tissues.
Target Research Area
others
Target Synonyms
hTPK1; Placental protein 20; PP20; Thiamin pyrophosphokinase 1; Thiamine diphosphokinase; Thiamine kinase; Thiamine pyrophosphokinase 1; THMD5; TPK1; TPK1_HUMAN
Target Background
The protein encoded by this gene functions as a homodimer and catalyzes the conversion of thiamine to thiamine pyrophosphate, a cofactor for some enzymes of the glycolytic and energy production pathways. Defects in this gene are a cause of thiamine metabolism dysfunction syndrome-5.
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