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The antibody against STOX1 was raised in rabbit using the Recombinant Human Storkhead-box protein 1 protein (559-858AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against STOX1 was raised in rabbit using the Recombinant Human Storkhead-box protein 1 protein (559-858AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-19537A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | STOX1 |
| Target Synonyms | STOX1 antibody; C10orf24 antibody; Storkhead-box protein 1 antibody; Winged-helix domain-containing protein antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Storkhead-box protein 1 protein (559-858AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6ZVD7 |
Uniprot Id
Q6ZVD7
Target Species
Human
Target Name
STOX1
Target Full Name
Storkhead-box protein 1
Target Function
Involved in regulating the levels of reactive oxidative species and reactive nitrogen species and in mitochondrial homeostasis in the placenta. Required for regulation of inner ear epithelial cell proliferation via the AKT signaling pathway.; Involved in cell cycle regulation by binding to the CCNB1 promoter, up-regulating its expression and promoting mitotic entry. Induces phosphorylation of MAPT/tau.
Target Involvement
Pre-eclampsia/eclampsia 4 (PEE4)
Target Subcellular Location
[Isoform A]: Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.; [Isoform B]: Nucleus.; [Isoform C]: Nucleus, nucleolus.
Target Tissue Specificity
Expressed in placenta, including the invasive extravillus trophoblast cells.
Target Synonyms
STOX1; C10orf24; Storkhead-box protein 1; Winged-helix domain-containing protein
Target Background
Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including positive regulation of G2/M transition of mitotic cell cycle; positive regulation of protein phosphorylation; and regulation of gene expression. Located in centrosome; cytosol; and nuclear lumen. Implicated in pre-eclampsia. Biomarker of Alzheimer's disease.
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