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The antibody against CORO7 was raised in rabbit using the Recombinant Human Coronin-7 protein (630-900AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against CORO7 was raised in rabbit using the Recombinant Human Coronin-7 protein (630-900AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
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| Cat.No | ADC-22158A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CORO7 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Coronin-7 protein (630-900AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P57737 |
Uniprot Id
P57737
Target Species
Human
Target Name
CORO7
Target Full Name
Coronin-7
Target Function
F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking. May play a role in the maintenance of the Golgi apparatus morphology.
Target Subcellular Location
Golgi apparatus membrane. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle. Cytoplasm, cytosol. Note=Predominantly cytosolic. Detected on vesicle-like cytoplasmic structures and on the cis-Golgi. Not associated with actin filaments.
Target Protein Families
WD repeat coronin family
Target Tissue Specificity
Widely expressed. Expressed in the spleen, peripheral leukocytes, testes, brain, thymus and small intestine.
Target Synonyms
0610011B16Rik; 70 kDa WD repeat tumor rejection antigen homolog; CORO 7; Coro7; CORO7_HUMAN; Coronin-7; Coronin7; Crn7; FLJ22021; FLJ44188; POD1
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