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The antibody against KEL was raised in rabbit using the Recombinant Human Kell blood group glycoprotein protein (201-500AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against KEL was raised in rabbit using the Recombinant Human Kell blood group glycoprotein protein (201-500AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-24636A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KEL |
| Target Synonyms | KEL; Kell blood group glycoprotein; CD antigen CD238 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Kell blood group glycoprotein protein (201-500AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P23276 |
Uniprot Id
P23276
Target Species
Human
Target Name
KEL
Target Full Name
Kell blood group glycoprotein
Target Function
Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3.
Target Subcellular Location
Cell membrane; Single-pass type II membrane protein. Note=Spans the erythrocyte membrane, and is attached to the underlying cytoskeleton.
Target Protein Families
Peptidase M13 family
Target Tissue Specificity
Expressed at high levels in erythrocytes and testis (in Sertoli cells), and, at lower levels, in skeletal muscle, tonsils (in follicular dendritic cells), lymph node, spleen and appendix (at protein level). Also expressed in many adult and fetal nonerythr
Target Synonyms
KEL; Kell blood group glycoprotein; CD antigen CD238
Target Background
This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases.
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