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Rabbit anti-Human WDR36 Polyclonal Antibody

The antibody against WDR36 was raised in rabbit using the Synthetic peptide of Human WDR36 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-25505A

The antibody against WDR36 was raised in rabbit using the Synthetic peptide of Human WDR36 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-25505A ClonalityPolyclonal
Host SpeciesRabbitTarget NameWDR36
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBS
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthetic peptide of Human WDR36Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8NI36
Background Information
  • Uniprot Id

    Q8NI36

  • Target Species

    Human

  • Target Name

    WDR36

  • Target Full Name

    WD repeat-containing protein 36

  • Target Function

    Involved in the nucleolar processing of SSU 18S rRNA. Involved in T-cell activation and highly coregulated with IL2.

  • Target Involvement

    Glaucoma 1, open angle, G (GLC1G)

  • Target Subcellular Location

    Nucleus, nucleolus.

  • Target Tissue Specificity

    Expressed in heart, placenta, liver, skeletal muscle, kidney and pancreas. In ocular tissues, strong expression in iris, sclera, ciliary muscle, ciliary body, retina and optic nerve.

  • Target Synonyms

    WDR36; WD repeat-containing protein 36; T-cell activation WD repeat-containing protein; TA-WDRP

  • Target Background

    This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Mutations in this gene have been associated with adult-onset primary open-angle glaucoma (POAG).

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