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The antibody against SOX3 was raised in rabbit using the Synthetic peptide of Human SOX2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against SOX3 was raised in rabbit using the Synthetic peptide of Human SOX2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-25986A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SOX3 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human SOX2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P41225 |
Uniprot Id
P41225
Target Species
Human
Target Name
SOX3
Target Full Name
Transcription factor SOX-3
Target Function
Transcription factor required during the formation of the hypothalamo-pituitary axis. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Required also within the pharyngeal epithelia for craniofacial morphogenesis. Controls a genetic switch in male development. Is necessary for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.
Target Involvement
Panhypopituitarism X-linked (PHPX); Mental retardation, X-linked, with isolated growth hormone deficiency (MRXGH); 46,XX sex reversal 3 (SRXX3)
Target Subcellular Location
Nucleus.
Target Synonyms
GHDX; MRGH; PHP; PHPX; sox3; SOX3_HUMAN; SOXB; SRY (sex determining region Y)-box 3; SRY Box 3; SRY-related HMG-box gene 3; Transcription factor Sox-3
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