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The antibody against RERG was raised in rabbit using the Recombinant Human Ras-related and estrogen-regulated growth inhibitor protein (1-199AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against RERG was raised in rabbit using the Recombinant Human Ras-related and estrogen-regulated growth inhibitor protein (1-199AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human breast cancer using RERG Antibody at dilution of 1:1002
| Cat.No | ADC-32849A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RERG |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Ras-related and estrogen-regulated growth inhibitor protein (1-199AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96A58 |
Uniprot Id
Q96A58
Target Species
Human
Target Name
RERG
Target Full Name
Ras-related and estrogen-regulated growth inhibitor
Target Function
Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Small GTPase superfamily, Ras family
Target Tissue Specificity
Detected in heart, brain, placenta, lung, liver, skin, kidney and pancreas. Detected in estrogen receptor-positive breast-derived cell lines, but not in estrogen receptor-negative cell lines. Expression is decreased or lost in a significant proportion of
Target Synonyms
MGC15754 ; RAS like estrogen regulated growth inhibitor ; Ras related and estrogen regulated growth inhibitor ; Ras-related and estrogen-regulated growth inhibitor; Rerg; RERG_HUMAN; Weakly similar to N ras protein [H.sapiens]
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