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Rabbit anti-Human VIPR1 Polyclonal Antibody

The antibody against VIPR1 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human VPAC1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.

ADC-33809A

The antibody against VIPR1 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human VPAC1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.

$167.00

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Specifications


Cat.No ADC-33809A ClonalityPolyclonal
Host SpeciesRabbitTarget NameVIPR1
Target SynonymsVIPR1; Vasoactive intestinal polypeptide receptor 1; VIP-R-1; Pituitary adenylate cyclase-activating polypeptide type II receptor; PACAP type II receptor; PACAP-R-2; PACAP-R2; VPAC1FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, IF, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the C-terminal region of Human VPAC1.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP32241
Background Information
  • Uniprot Id

    P32241

  • Target Species

    Human

  • Target Name

    VIPR1

  • Target Full Name

    Vasoactive intestinal polypeptide receptor 1

  • Target Function

    This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The affinity is VIP = PACAP-27 > PACAP-38.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    G-protein coupled receptor 2 family

  • Target Tissue Specificity

    In lung, HT-29 colonic epithelial cells, Raji B-lymphoblasts. Lesser extent in brain, heart, kidney, liver and placenta. Not expressed in CD4+ or CD8+ T-cells. Expressed in the T-cell lines HARRIS, HuT 78, Jurkat and SUP-T1, but not in the T-cell lines Pe

  • Target Synonyms

    VIPR1; Vasoactive intestinal polypeptide receptor 1; VIP-R-1; Pituitary adenylate cyclase-activating polypeptide type II receptor; PACAP type II receptor; PACAP-R-2; PACAP-R2; VPAC1

  • Target Background

    This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene.

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