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The antibody against SIRPG was raised in rabbit using the Synthesized peptide derived from the Internal region of Human CD172g. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against SIRPG was raised in rabbit using the Synthesized peptide derived from the Internal region of Human CD172g. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
| Cat.No | ADC-34564A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SIRPG |
| Form | Liquid | Species Reactivity | Human, Monkey |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human CD172g. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9P1W8 |
Uniprot Id
Q9P1W8
Target Species
Human
Target Name
SIRPG
Target Full Name
Signal-regulatory protein gamma
Target Function
Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Tissue Specificity
Detected in liver, and at very low levels in brain, heart, lung, pancreas, kidney, placenta and skeletal muscle. Expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD20+ cells, and all activated NK cells. Mainly present in the
Target Research Area
Immunology
Target Synonyms
D172 antigen like family member B; bA77C3.1; CD172 antigen-like family member B; CD172g; CD172g antigen; FLJ42230; RP11-77C3.2; Signal regulatory protein beta 2; Signal regulatory protein gamma; Signal-regulatory protein beta-2; Signal-regulatory protein gamma; SIRP B2; SIRP beta 2; SIRP gamma; SIRP-b2; SIRP-beta-2; SIRP-gamma; SIRPB2; SIRPG; SIRPG_HUMAN; SIRPgamma
Target Background
The protein encoded by this gene is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described.
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