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The antibody against TRPC3 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human TRPC3. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against TRPC3 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human TRPC3. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
Western Blot analysis of HeLa cells using TRPC3 Polyclonal Antibody
| Cat.No | ADC-36855A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TRPC3 |
| Target Synonyms | TRPC3 antibody; TRP3 antibody; Short transient receptor potential channel 3 antibody; TrpC3 antibody; Transient receptor protein 3 antibody; TRP-3 antibody; hTrp-3 antibody; hTrp3 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human TRPC3. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q13507 |
Uniprot Id
Q13507
Target Species
Human
Target Name
TRPC3
Target Full Name
Short transient receptor potential channel 3
Target Function
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol 1,4,5-triphosphate receptors (ITPR) with bound IP3. May also be activated by internal calcium store depletion.
Target Involvement
Spinocerebellar ataxia 41 (SCA41)
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Transient receptor (TC 1.A.4) family, STrpC subfamily, TRPC3 sub-subfamily
Target Tissue Specificity
Expressed predominantly in brain and at much lower levels in ovary, colon, small intestine, lung, prostate, placenta and testis.
Target Synonyms
TRPC3; TRP3; Short transient receptor potential channel 3; TrpC3; Transient receptor protein 3; TRP-3; hTrp-3; hTrp3
Target Background
The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene.
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