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Rabbit anti-Human PAH Polyclonal Antibody

The antibody against PAH was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human PAH. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

ADC-37909A

The antibody against PAH was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human PAH. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-37909A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePAH
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the C-terminal region of Human PAH.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP00439
Background Information
  • Uniprot Id

    P00439

  • Target Species

    Human

  • Target Name

    PAH

  • Target Full Name

    Phenylalanine-4-hydroxylase

  • Target Function

    Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine.

  • Target Involvement

    Phenylketonuria (PKU); Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA); Hyperphenylalaninemia (HPA)

  • Target Protein Families

    Biopterin-dependent aromatic amino acid hydroxylase family

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    PAH; PH; PH4H_HUMAN; Phe 4 monooxygenase; Phe-4-monooxygenase; Phenylalanine 4 hydroxylase; Phenylalanine hydroxylase; Phenylalanine-4-hydroxylase; PKU; PKU1

  • Target Background

    This gene encodes a member of the biopterin-dependent aromatic amino acid hydroxylase protein family. The encoded phenylalanine hydroxylase enzyme hydroxylates phenylalanine to tyrosine and is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria.

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