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The antibody against MRAP was raised in rabbit using the Recombinant Human Melanocortin-2 receptor accessory protein (59-172AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
The antibody against MRAP was raised in rabbit using the Recombinant Human Melanocortin-2 receptor accessory protein (59-172AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
$299.00
| Cat.No | ADC-04684A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MRAP |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | FITC conjugated |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Melanocortin-2 receptor accessory protein (59-172AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8TCY5 |
Uniprot Id
Q8TCY5
Target Species
Human
Target Name
MRAP
Target Full Name
Melanocortin-2 receptor accessory protein
Target Function
Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH). May be involved in the intracellular trafficking pathways in adipocyte cells.
Target Involvement
Glucocorticoid deficiency 2 (GCCD2)
Target Subcellular Location
Cell membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Target Protein Families
MRAP family
Target Tissue Specificity
Expressed in adrenal cortex, testis, breast, thyroid, lymph node, ovary and fat. Expressed in adipose tissues.
Target Synonyms
B27; C21orf61; FALP; Fat cell-specific low molecular weight protein; Fat tissue-specific low MW protein; FGD2; GCCD2; Melanocortin-2 receptor accessory protein; Mrap; MRAP_HUMAN
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