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Rabbit anti-Human AKAP1 Polyclonal Antibody

The antibody against AKAP1 was raised in rabbit using the Synthetic peptide corresponding to a region derived from internal residues of Human A kinase (PRKA) anchor protein 1 as the immunogen. This antibody exists as a polyclonal antibody to the immunogen, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-40633A

The antibody against AKAP1 was raised in rabbit using the Synthetic peptide corresponding to a region derived from internal residues of Human A kinase (PRKA) anchor protein 1 as the immunogen. This antibody exists as a polyclonal antibody to the immunogen, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$297.00

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Specifications


Cat.No ADC-40633A ClonalityPolyclonal
Host SpeciesRabbitTarget NameAKAP1
FormLiquidSpecies ReactivityHuman, Mouse, Rat
Storage Buffer0.05% NaN3, 50% Glycerol, Rabbit IgG in pH7.3 PBSPurification MethodAntigen affinity purified
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthetic peptide corresponding to a region derived from internal residues of Human A kinase (PRKA) anchor protein 1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ92667
Background Information
  • Uniprot Id

    Q92667

  • Target Species

    Human

  • Target Name

    AKAP1

  • Target Full Name

    A-kinase anchor protein 1, mitochondrial

  • Target Function

    Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane. Involved in mitochondrial-mediated antiviral innate immunity. Promotes translocation of NDUFS1 into mitochondria to regulate mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) activity.

  • Target Subcellular Location

    Mitochondrion outer membrane. Mitochondrion.

  • Target Tissue Specificity

    Isoform 1 is detected in thymus, prostate, testis, ovary, colon and small intestine. Isoform 2 is highly expressed in testis and detected at much lower levels in kidney, pancreas, liver, lung and brain.

  • Target Synonyms

    A kinase anchor protein; A-kinase anchor protein 1; A-kinase anchor protein 149 kDa; AKAP 149; AKAP; Akap1; AKAP1_HUMAN; D-AKAP-1; DAKAP1; Dual specificity A-kinase-anchoring protein 1; mitochondrial; PRKA1; Protein kinase A-anchoring protein 1; Protein kinase A1; S-AKAP84; SAKAP84; Spermatid A-kinase anchor protein 84

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