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The antibody against SRCIN1 was raised in rabbit using the Synthesized peptide derived from internal of Human SNIP. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against SRCIN1 was raised in rabbit using the Synthesized peptide derived from internal of Human SNIP. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from HepG2 and HeLa cells, using SNIP antibody.
| Cat.No | ADC-40737A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SRCIN1 |
| Form | Liquid | Species Reactivity | Human |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human SNIP. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9C0H9 |
Uniprot Id
Q9C0H9
Target Species
Human
Target Name
SRCIN1
Target Full Name
SRC kinase signaling inhibitor 1
Target Function
Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance.
Target Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Cell junction, synapse, presynapse. Cell junction, synapse, postsynapse. Cell junction, synapse, postsynaptic density.
Target Protein Families
SRCIN1 family
Target Tissue Specificity
Expressed in some primary breast carcinomas where its presence is significantly associated with increased tumor size. Not detected in normal breast tissue.
Target Synonyms
p130Cas associated protein; p130Cas-associated protein; P140; p140Cap; SNAP-25-interacting protein; SNIP; SRC kinase signaling inhibitor 1; SRCIN1; SRCN1_HUMAN
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