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The antibody against FLOT2 was raised in rabbit using the Peptide sequence around aa.420~424(I-K-K-A-T) derived from Human ESA (FLOT2). as the immunogen. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. This antibody has been validated on ELISA, WB.
The antibody against FLOT2 was raised in rabbit using the Peptide sequence around aa.420~424(I-K-K-A-T) derived from Human ESA (FLOT2). as the immunogen. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. This antibody has been validated on ELISA, WB.
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Western blot analysis of extract from JK, HUVEC, HepG2 and Hela cells using ESA(FLOT2) Antibody
| Cat.No | ADC-43195A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FLOT2 |
| Form | Liquid | Species Reactivity | Human |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Peptide sequence around aa.420~424(I-K-K-A-T) derived from Human ESA (FLOT2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q14254 |
Uniprot Id
Q14254
Target Species
Human
Target Name
FLOT2
Target Full Name
Flotillin-2
Target Function
May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.
Target Subcellular Location
Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Endosome. Membrane; Lipid-anchor. Note=Membrane-associated protein of caveolae.
Target Protein Families
Band 7/mec-2 family, Flotillin subfamily
Target Tissue Specificity
In skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carci
Target Research Area
Neuroscience
Target Synonyms
ECS-1; ECS1; Epidermal surface antigen 1; Epidermal surface antigen; ESA; ESA1; Flot2; FLOT2_HUMAN; Flotillin 2 (epidermal surface antigen 1); Flotillin-2; M17S1; Membrane component chromosome 17 surface marker 1; Membrane component chromosome 17 surface marker 1 homolog; membrane component; chromosome 17; surface marker 1 (35kD protein identified by monoclonal ECS-1); Membrane component; chromosome 17; surface marker 1; REG-1; Reggie-1; Reggie-2
Target Background
Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. This gene encodes a caveolae-associated, integral membrane protein, which is thought to function in neuronal signaling.
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