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The antibody against TIAF1 was raised in rabbit using the Recombinant Human TGFB1-induced anti-apoptotic factor 1 protein (1-115AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against TIAF1 was raised in rabbit using the Recombinant Human TGFB1-induced anti-apoptotic factor 1 protein (1-115AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human skin tissue using TIAF1 Antibody at dilution of 1:100
| Cat.No | ADC-44344A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TIAF1 |
| Target Synonyms | TIAF1 antibody; TGFB1-induced anti-apoptotic factor 1 antibody; 12 kDa TGF-beta-1-induced antiapoptotic factor antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human TGFB1-induced anti-apoptotic factor 1 protein (1-115AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O95411 |
Uniprot Id
O95411
Target Species
Human
Target Name
MYO18A
Target Full Name
Putative TGFB1-induced anti-apoptotic factor 1
Target Function
Inhibits the cytotoxic effects of TNF-alpha and overexpressed TNF receptor adapters TRADD, FADD, and RIPK1. Involved in TGF-beta1 inhibition of IkappaB-alpha expression and suppression of TNF-mediated IkappaB-alpha degradation.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Not detectable in normal kidney and liver. Up-regulated in chronic and acute allograft rejection: expressed in the inflammatory infiltrate and in tubular epithelial cells.
Target Research Area
Cell Biology
Target Synonyms
TIAF1; TGFB1-induced anti-apoptotic factor 1; 12 kDa TGF-beta-1-induced antiapoptotic factor
Target Background
Inhibits the cytotoxic effects of TNF-alpha and overexpressed TNF receptor adapters TRADD, FADD, and RIPK1. Involved in TGF-beta1 inhibition of IkappaB-alpha expression and suppression of TNF-mediated IkappaB-alpha degradation.
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