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The antibody against ORF3 was raised in rabbit using the Recombinant Hepatitis E virus genotype 1 Protein ORF3 protein (1-114AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against ORF3 was raised in rabbit using the Recombinant Hepatitis E virus genotype 1 Protein ORF3 protein (1-114AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-45520A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ORF3 |
| Target Synonyms | ORF3 antibody; Protein ORF3 antibody; pORF3 antibody | Form | Liquid |
| Species Reactivity | Hepatitis E virus genotype 1 | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Hepatitis E virus genotype 1 Protein ORF3 protein (1-114AA) | Target Species | Hepatitis E virus genotype 1 |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O90299 |
Uniprot Id
O90299
Target Species
Hepatitis E virus genotype 1
Target Name
ORF3
Target Function
Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway. Acts also as a viroporin and forms ion conductive pores allowing viral particle release. Impairs the generation of type I interferon by downregulating host TLR3 and TLR7 as well as their downstream signaling pathways.
Target Subcellular Location
Host endoplasmic reticulum membrane. Host cytoplasm.
Target Protein Families
Hepevirus ORF3 protein family
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