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The antibody against ATOH1 was raised in rabbit using the Recombinant Human Protein atonal homolog 1 protein (1-354AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against ATOH1 was raised in rabbit using the Recombinant Human Protein atonal homolog 1 protein (1-354AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human testis tissue using ATOH1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using ATOH1 Antibody at dilution of 1:1002
| Cat.No | ADC-45730A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Atoh1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Protein atonal homolog 1 protein (1-354AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q92858 |
Uniprot Id
Q92858
Target Species
Human
Target Name
ATOH1
Target Full Name
Transcription factor ATOH1
Target Function
Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription.
Target Subcellular Location
Nucleus.
Target Research Area
Epigenetics and Nuclear Signaling, Developmental Biology
Target Synonyms
ATH1; ATOH1; ATOH1_HUMAN; Atonal homolog 1 (Drosophila); Atonal homolog 1; bHLHa14; Class A basic helix-loop-helix protein 14; hATH1; Helix loop helix protein hATH 1; Helix-loop-helix protein hATH-1; MATH 1; MATH1; Protein atonal homolog 1
Target Background
Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in neuron differentiation; positive regulation of neuron differentiation; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including generation of neurons; inner ear morphogenesis; and positive regulation of inner ear auditory receptor cell differentiation. Predicted to be part of chromatin. Predicted to be active in nucleus.
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