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The antibody against KLC2 was raised in rabbit using the Human KLC2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against KLC2 was raised in rabbit using the Human KLC2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-48160A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KLC2 |
| Target Synonyms | Kinesin light chain 2 antibody; KLC 2 antibody; KLC2 antibody; KLC2_HUMAN antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human KLC2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H0B6 |
Uniprot Id
Q9H0B6
Target Species
Human
Target Name
KLC2
Target Full Name
Kinesin light chain 2
Target Function
Kinesin is a microtubule-associated force-producing protein that plays a role in organelle transport. The light chain functions in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (Probable). Through binding with PLEKHM2 and ARL8B, recruits kinesin-1 to lysosomes and hence direct lysosomes movement toward microtubule plus ends.
Target Involvement
Spastic paraplegia, optic atrophy, and neuropathy (SPOAN)
Target Subcellular Location
Cytoplasm, cytoskeleton. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side.
Target Protein Families
Kinesin light chain family
Target Synonyms
Kinesin light chain 2; KLC 2; KLC2; KLC2_HUMAN
Target Background
The protein encoded by this gene is a light chain of kinesin, a molecular motor responsible for moving vesicles and organelles along microtubules. Defects in this gene are a cause of spastic paraplegia, optic atrophy, and neuropathy (SPOAN) syndrome.
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