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The antibody against DYM was raised in rabbit using the Human DYM as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against DYM was raised in rabbit using the Human DYM as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-48699A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DYM |
| Target Synonyms | DYMDymeclin antibody; Dyggve-Melchior-Clausen syndrome protein antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human DYM | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q7RTS9 |
Uniprot Id
Q7RTS9
Target Species
Human
Target Name
DYM
Target Full Name
Dymeclin
Target Function
Necessary for correct organization of Golgi apparatus. Involved in bone development.
Target Involvement
Dyggve-Melchior-Clausen syndrome (DMC); Smith-McCort dysplasia 1 (SMC1)
Target Subcellular Location
Cytoplasm. Golgi apparatus. Membrane; Lipid-anchor. Note=Sequence analysis programs clearly predict 1 transmembrane region. However, PubMed:18996921 shows that it is not a stably anchored transmembrane protein but it weakly associates with the Golgi apparatus and shuttles between the Golgi and the cytosol.
Target Protein Families
Dymeclin family
Target Tissue Specificity
Expressed in most embryo-fetal and adult tissues. Abundant in primary chondrocytes, osteoblasts, cerebellum, kidney, lung, stomach, heart, pancreas and fetal brain. Very low or no expression in the spleen, thymus, esophagus, bladder and thyroid gland.
Target Synonyms
DYMDymeclin; Dyggve-Melchior-Clausen syndrome protein
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