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The antibody against NPTX2 was raised in rabbit using the Human NPTX2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against NPTX2 was raised in rabbit using the Human NPTX2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-52533A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NPTX2 |
| Target Synonyms | neuronal antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human NPTX2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P47972 |
Uniprot Id
P47972
Target Species
Human
Target Name
NPTX2
Target Full Name
Neuronal pentraxin-2
Target Function
Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner.
Target Subcellular Location
Secreted.
Target Tissue Specificity
Brain, pancreas, liver, heart and skeletal muscle. Highest levels are seen in the testis.
Target Synonyms
apexin; NARP; neuronal activity-regulated pentaxin; Neuronal pentraxin 2; Neuronal pentraxin II; Neuronal pentraxin-2; NP 2; NP-II; NP2; NPII ; NPTX2; NPTX2_HUMAN; pentraxin II, neuronal
Target Background
This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.
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