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The antibody against KLHL21 was raised in rabbit using the Human KLHL21 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against KLHL21 was raised in rabbit using the Human KLHL21 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-52926A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KLHL21 |
| Target Synonyms | Kelch-like protein 21 antibody; KIAA0469 antibody; KLH21_HUMAN antibody; KLHL21 antibody; MGC99635 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human KLHL21 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UJP4 |
Uniprot Id
Q9UJP4
Target Species
Human
Target Name
KLHL21
Target Full Name
Kelch-like protein 21
Target Function
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
Target Subcellular Location
Cytoplasm, cytoskeleton, spindle. Note=Localizes to the spindle midzone and targets CUL3 to this region.
Target Synonyms
Kelch-like protein 21; KIAA0469; KLH21_HUMAN; KLHL21; MGC99635
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