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The antibody against GTSE1 was raised in rabbit using the Human GTSE1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.
The antibody against GTSE1 was raised in rabbit using the Human GTSE1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.
$600.00
| Cat.No | ADC-53170A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GTSE1 |
| Target Synonyms | GTSE1 antibody; G2 and S phase-expressed protein 1 antibody; GTSE-1 antibody; Protein B99 homolog antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Human GTSE1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NYZ3 |
Uniprot Id
Q9NYZ3
Target Species
Human
Target Name
GTSE1
Target Full Name
G2 and S phase-expressed protein 1
Target Function
May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression.
Target Subcellular Location
Cytoplasm, cytoskeleton. Note=Associated with microtubules.
Target Synonyms
GTSE1; G2 and S phase-expressed protein 1; GTSE-1; Protein B99 homolog
Target Background
The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.
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