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The antibody against DCTN6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human DCTN6 (NP_006562.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against DCTN6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human DCTN6 (NP_006562.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01523A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DCTN6 |
| Target Synonyms | WS3; p27; WS-3; DCTN6 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 22Rv1, A-549, Mouse brain, Mouse thymus, U-251MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human DCTN6 (NP_006562.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MAEKTQKSVKIAPGAVVCVESEIRGDVTIGPRTVIHPKARIIAEAGPIVIGEGNLIEEQALIINAYPDNITPDTEDPEPKPMIIGTNNVFEVGCYSQAMKMGDNNVIESKAYVGRNVILTSGCIIGACCNLNTFEVIPENTVIYGADCLRRVQTERPQPQTLQLDFLMKILPNYHHLKKTMKGSSTPVKN | Uniprot ID | O00399 |
Uniprot Id
O00399
Target Species
Human
Target Name
DCTN6
Target Full Name
Dynactin subunit 6
Target Subcellular Location
Cytoplasm, cytoskeleton. Chromosome, centromere, kinetochore.
Target Protein Families
Dynactin subunits 5/6 family, Dynactin subunit 6 subfamily
Target Tissue Specificity
Ubiquitous.
Target Research Area
Cell Biology
Target Synonyms
DCTN6; DCTN6_HUMAN; Dynactin 6; Dynactin subunit 6; Dynactin subunit p27; Novel RGD containing protein; p27; Protein WS-3; Protein WS3; WS 3; WS3
Target Background
The protein encoded by this gene contains an RGD (Arg-Gly-Asp) motif in the N-terminal region, which confers adhesive properties to macromolecular proteins like fibronectin. It shares a high degree of sequence similarity with the mouse homolog, which has been suggested to play a role in mitochondrial biogenesis. The exact biological function of this gene is not known.
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