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The antibody against TFPT was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-253 of human TFPT (NP_037474.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against TFPT was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-253 of human TFPT (NP_037474.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
Immunofluorescence analysis of U2OS cells using TFPT antibody.
| Cat.No | ADA-03010A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TFPT |
| Target Synonyms | FB1; amida; INO80F; TFPT | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-253 of human TFPT (NP_037474.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P0C1Z6 | Immunogen Sequence |
Uniprot Id
P0C1Z6
Target Species
Human
Target Name
TFPT
Target Full Name
TCF3 fusion partner
Target Function
Appears to promote apoptosis in a p53/TP53-independent manner.; Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
Target Involvement
A chromosomal aberration involving TFPT is a cause of pre-B-cell acute lymphoblastic leukemia (B-ALL). Inversion inv(19)(p13;q13) with TCF3.
Target Subcellular Location
Nucleus.
Target Synonyms
Amida; INO80 complex subunit F; INO80F; Protein FB1; TCF3 (E2A) fusion partner (in childhood Leukemia); TCF3 fusion partner; TFPT; TFPT_HUMAN
Target Background
Predicted to enable DNA binding activity and protein kinase binding activity. Involved in apoptotic signaling pathway. Located in nucleoplasm. Part of Ino80 complex.
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